Paul A. Pham Pharm.D. and John G. Bartlett M.D.
Available formulation in Zambia: Tablet (chewable): 100 mg; 500 mg.
- Well-tolerated oral agent with comparable anthelminthic properties compared to albendazole, but appears to be more effective against whipworm (Trichuris trichiura).
Zambia Information Author: Paul A. Pham, Pharm. D.
- Enterobiasis (pinworm),
- Ascariasis (roundworm)
- Trichuriasis (whipworm)
- Echinococcus (second line)
|Vermox||Mebendazole||Various generic manufacturers ||PO|
*Prices represent cost per unit specified and are representative of "Average Wholesale Price" (AWP).
AWP Prices were obtained and gathered by Lakshmi Vasist Pharm D using the Red Book, manufacturer's
information, and the McKesson database.
^Dosage is indicated in mg unless otherwise noted.
- Roundworm (ascaris):100-200 mg PO twice daily x 5 d or 500mg PO x 1.
- Hookworm: 100mg PO twice daily x 3 days or 500mg PO x 1.
- Pinworm: 100mg PO x 1 (may be repeated if infection persists for 3 weeks).
- Echinococcus: 40-50 mg/kg/d in 3 divided doses
Drug concentration not affected by dialysis; use usual dose.
Carbamazepine: may decrease mebendazole serum levels. Consider valproic acid with co-administration.
, Enterobius vermicularis (pinworm), Trichuris trichiura (whipworm), Ascaris lumbricoides (common roundworm), Ancylostoma duodenale (common hookworm), Necator americanus (American hookworm)
Well-tolerated oral agent with broad-spectrum antihelmintic. Mean cure rates are >95% for pinworm, roundworm, and hookworm infections, and 35-68% for whipworm infection.