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Paul A. Pham Pharm.D. and John G. Bartlett M.D.
05-21-2009
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Available formulation in Zambia: Pyrantel Oral liquid: 50 mg/ml (as embonate). Tablet (chewable): 250 mg (as embonate).
- Active against many nematodes
- Ascariasis, enterobiasis, trichostrongyliasis: 11 mg/kg base PO x1 (max 1 g/day)
- Infection by Moniliformis: 11 mg/kg base PO x1; repeat twice, at 2-wk intervals
- Infection by Uncinaria: 11 mg/kg base daily x3 d (max 1 g/day)
Zambia Information Author: Paul A. Pham Pharm.D.
- Ascariasis
- Enterobiasis
- Helminth infections
- Trichostrongylus infections
brand
name
| generic
| Mfg
| brand
forms
| cost*
|
| Pin-X | Pyrantel pamoate | Penn labs | oral
solution
144mg/ml (30ml) | $8.47 |
*Prices represent cost per unit specified and are representative of "Average Wholesale Price" (AWP).
AWP Prices were obtained and gathered by Lakshmi Vasist Pharm D using the Red Book, manufacturer's
information, and the McKesson database.
^Dosage is indicated in mg unless otherwise noted.
11mg/kg PO x 1 dose (max 1gm).
No data, usually dose likely since less than 7% excreted in the urine.
No data, usually dose likely since less than 7% excreted in the urine.
No data, usually dose likely since less than 7% excreted in the urine.
No data.
No data.
No data.
- Piperazine: antagonism with co-administration. Avoid co-administration.
- Theophylline: theophylline serum concentrations may be decreased. Monitor theophylline serum concentrations closely with co-administration.
Hookworm (Ancylostoma duodenale, Necator americanus), pinworms (Enterobius vermicularis), roundworm (Ascariasis lumbricoides), Ancylostoma caninum
Well-tolerated agent active against many nematodes. Should not be used together with piperazine due to antagonism.
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