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HIV Guide
 Zambia HIV National Guidelines
 


Introduction  

HIV Counseling and Testing  

Sexually Transmitted Infections (STIs)  

General Principles of Antiretroviral Therapy for Chronic HIV Infection in Adults and Adolescents  

When to Start ARV Therapy for Chronic HIV Infection in Adults and Adolescents  

Initial Regimen for ARV Therapy  

Adherence  

Baseline evaluation and Monitoring  

Calculations: Ideal Body Weight, Body Mass Index and Creatinine Clearance  

ARV Therapy for Individuals with Tuberculosis Co-Infection  

Adverse Effects and Toxicity  

Immune Reconstitution Inflammatory Syndrome (IRIS)  

Changing or Stopping ART  

Treatment Failure  

Stopping ARV Therapy  

Post Exposure Prophylaxis  

Cotrimoxazole Prophylaxis  

WHO Staging in Adults and Adolescents  

Nutrition Care and Support  

Palliative Care in HIV and AIDS  

 Guide Editors
 Editor In Chief
    Joel E. Gallant, MD, MPH

Pharmacology Editor
    Paul Pham, PharmD, BCPS

Zambia Guideline Team
   Peter Mwaba MMed PhD FRCP
   Alywn Mwinga MMed
   Isaac Zulu MMed MPH
   Velepie Mtonga MMed
   Albert Mwango MBChB
   Jabbin Mulwanda MMed FCS
 

 

 

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Diagnosis

Complications of Therapy
 Diabetes Mellitus and Insulin Resistance  
 Hepatotoxicity  
 Hyperlipidemia  
 Immune reconstitution inflammatory syndrome (IRIS)  
 Lactic Acidosis  
 Lipodystrophy  
Malignancies
 Kaposi's sarcoma  
 Lymphoma, Hodgkins  
 Lymphoma, Non-Hodgkins (NHL)  
 Lymphoma, Primary CNS (PCNSL)  
Miscellaneous
 Primary HIV Infection  
Opportunistic Infections
 Candidiasis, esophageal  
 Candidiasis, oropharyngeal  
 Candidiasis, vulvovaginal  
 CMV, gastrointestinal  
 CMV, neurologic  
 CMV retinitis  
 Cryptococcal Meningitis  
 Cryptosporidiosis  
 Hepatitis A  
 Hepatitis B  
 Hepatitis C  
 Herpes simplex  
 Herpes zoster  
 Microsporidiosis  
 Mycobacterium avium complex (MAC), disseminated  
 Nocardiosis  
 Peliosis hepatis  
 Pneumocystis carinii pneumonia  
 Pneumonia, bacterial  
 Progressive multifocal leukoencephalopathy (PML)  
 Syphilis  
 Toxoplasmosis  
 Tuberculosis, Active (Zambia specific)  
 Tuberculosis, Resistant (Zambia specific)  
Organ System
 Anemia  
 Aphthous ulcers  
 Bacillary angiomatosis  
 Cardiac Manifestations of HIV Infections  
 Cholangiopathy, HIV  
 Dementia, HIV-Associated (HAD)  
 Depression  
 Diarrhea  
 Folliculitis  
 Gingivitis/periodontitis  
 Lymphoid interstitial pneumonitis  
 Molluscum contagiosum  
 Muscle Disorders  
 Nausea/Vomiting  
 Nephropathy, HIV-Associated (HIVAN)  
 Neuropathy, peripheral  
 Neutropenia  
 Osteoporosis  
 Pancreatitis  
 Pneumothorax  
 Salivary gland disorders  
 Seborrhea  
 Sinusitis  
 Thrombocytopenia  
 Thrombotic thrombocytopenic purpura  
 Wasting  

Drugs

Antimicrobial Agents
 Acyclovir  
 Albendazole  
 Amikacin  
 Amodiaquine  
 Amoxycillin  
 Amoxycillin-Clavulanic Acid  
 Amphotericine  
 Ampicillin  
 artemether/lumefantrine  
 Azithromycin  
 Benzathine Penicllin  
 benzyl penicillin  
 Cefazolin  
 Cefotaxime  
 Ceftazidime  
 Ceftriazone  
 Cefuroxime  
 Cephalexin  
 Chloramphenicol  
 Chloroquine  
 Ciprofloxacin  
 Clarithromycin  
 Clindamycin  
 Clotrimazole  
 Cloxacillin  
 Cotrimoxazole  
 Dapsone  
 Diethyl-carbamazine  
 Doxycycline  
 Erythromycin  
 Ethambutol  
 Ethionamide  
 Flucloxacillin  
 Fluconazole  
 Flucytosine  
 Ganciclovir  
 Gentamicin  
 Griseofulvin  
 Isoniazid  
 Kanamycin  
 Levofloxacin  
 Mebendazole  
 Melarsoprol  
 Metronidazole  
 Miconazole Nitrate  
 Nalidixic Acid  
 Niclosamide  
 Nitrofurantoin  
 Norfloxacin  
 Nystatin  
 Ofloxacin  
 Penicillin  
 phenoxymethyl penicillin  
 Piperacin  
 Praziquantel  
 Primaquine  
 Proguanil  
 Pyrantel  
 Pyrazinamide  
 Pyrimethamine  
 Quinine  
 Rifampicin  
 Spectinomycin  
 Streptomycin  
 Sulfadiazine  
 Sulfadoxine-pyrimethamine  
 Suramin  
 Tetracycline  
 Ticarcillin  
 Tinidazole  
 Trimethoprim  
 Valganciclovir  
 Vancomycin  
Antiretrovirals
 Abacavir  
 Atazanavir  
 Darunavir  
 Delavirdine  
 Didanosine  
 Efavirenz  
 Emtricitabine  
 Enfuvirtide  
 Etravirine  
 Fosamprenavir  
 Indinavir  
 Lamivudine  
 Lopinavir/Ritonavir  
 Maraviroc  
 Nelfinavir  
 Nevirapine  
 Ritonavir  
 Saquinavir  
 Stavudine  
 Tenofovir  
 Tipranavir  
 Zidovudine  
Miscellaneous
 glucocorticoids  
 leucovorin  

Guidelines

Zambia HIV National Guidelines
 Adherence  
 Adverse Effects and Toxicity  
 ARV Therapy for Individuals with Tuberculosis Co-Infection  
 Baseline evaluation and Monitoring  
 Calculations: Ideal Body Weight, Body Mass Index and Creatinine Clearance  
 Changing or Stopping ART  
 Cotrimoxazole Prophylaxis  
 General Principles of Antiretroviral Therapy for Chronic HIV Infection in Adults and Adolescents  
 HIV Counseling and Testing  
 Immune Reconstitution Inflammatory Syndrome (IRIS)  
 Initial Regimen for ARV Therapy  
 Introduction  
 Nutrition Care and Support  
 Palliative Care in HIV and AIDS  
 Post Exposure Prophylaxis  
 Sexually Transmitted Infections (STIs)  
 Stopping ARV Therapy  
 Treatment Failure  
 When to Start ARV Therapy for Chronic HIV Infection in Adults and Adolescents  
 WHO Staging in Adults and Adolescents  

Management

Antiretroviral Therapy
 Adherence  
 Post-exposure prophylaxis  
 Pregnancy and perinatal transmission (Zambia specific)  
 Toxicity & side effects: switching therapy (Zambia specific)  
 Treatment interruption  
Laboratory Testing
 Baseline & routine testing  
 CD4 Cell Count  
 HIV Diagnosis  
Miscellaneous
 Initial Evaluation (Zambia specific)  

Pathogens

Bacteria
 Chlamydia trachomatis  
 Clostridium difficile  
 Haemophilus influenzae  
 Listeria monocytogenes  
 Mycobacterium kansasii  
 Mycobacterium spp.  
 Neisseria gonorrhoeae  
 Pseudomonas aeruginosa  
 Rhodococcus equi  
 Salmonella spp.  
 Staphylococcus spp.  
 Streptococcus pneumoniae  
Fungi
 Aspergillus spp.  
 Blastomyces dermatitidis  
 Candida spp.  
Parasites
 Cyclospora cayetanensis  
 Entamoeba histolytica  
 Giardia lamblia  
 Isospora belli  
 Leishmania species  
 Trichomonas vaginalis  
Viruses
 Cytomegalovirus  
 Epstein-Barr virus  
 HHV-8  
 HTLV I/II  
 Human papillomavirus (HPV)  

 
Diagnosis
 


Complications of Therapy


Malignancies


Miscellaneous


Opportunistic Infections


Organ System

Drugs
 


Antimicrobial Agents


Antiretrovirals


Miscellaneous

Guidelines
 


Zambia HIV National Guidelines

Management
 


Antiretroviral Therapy


Laboratory Testing


Miscellaneous

Pathogens
 


Bacteria


Fungi


Parasites


Viruses

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